Thursday, 2 July 2015

Non-Hodgkins Lymphoma Involving Multiple Cardiac Chambers with Skeletal Muscle Involvement in a Hepatitis C Positive Patient

Primary cardiac lymphomas are rare and involvement of multiple cardiac chambers is not common. It usually invades primarily the right atrium, followed by the right ventricle, the left ventricle, and finally the atrial septum. Skeletal muscle involvement is also rare. FDG PET Scan is useful in diagnosis and in determining the disease extent, site for biopsy and its response to treatment.


We present a rare case of a Primary Cardiac Lymphoma in a Hepatitis C positive male which developed 3 years after he underwent CABG Surgery, which involved the right atrium, inter-atrial septum and left atrium and prolapsed across the tricuspid valve into the right ventricle. Additionally there was involvement of the Internal Oblique muscle that was proven on biopsy. FDG PET CT Scan was a useful guide to determine the extent of involvement, select the site of biopsy and evaluate the response to chemotherapy.

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